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filingDate 2018-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109096082-B
titleOfInvention Method for synthesizing alpha-iodo-cyclopentenone compound
abstract The invention discloses a method for synthesizing alpha-iodo-cyclopentenone compounds, which comprises the steps of adding enyne ester and gold (I) hexafluoroantimonate into methyl tert-butyl ether solution, stirring for 1 hour, confirming that all raw materials completely react through TLC, and then adding N-iodo-succinimide. The invention provides a method for synthesizing alpha-iodo-cyclopentenone compounds from acyclic enyne ester compounds. The whole reaction is carried out at normal temperature and normal pressure, and has the advantages of simple and convenient operation, mild conditions, good substrate functional group compatibility, high product yield, easy separation of the catalyst and the product and the like. The developed alpha-iodo-cyclopentenone compound has high reaction activity and can be used as an important organic intermediate to be applied to the fields of medicines, pesticides, synthesis of natural products and the like.
priorityDate 2018-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 50.