http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109081836-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1092 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1029 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-643 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6447 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6486 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 |
filingDate | 2018-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109081836-B |
titleOfInvention | Mercury ion near-infrared fluorescent probe based on hemicyanine structure and preparation method and application thereof |
abstract | The invention provides a mercury ion near-infrared fluorescent probe based on a hemicyanine structure, which has the following structural formula: the probe is based on a mercuric ion induced thioacetal deprotection mechanism, hemicyanine is taken as a matrix, a hemicyanine dye molecular monomer is released after the interaction with mercuric ions, the fluorescence intensity is obviously enhanced and is accompanied with obvious color change, the probe can be used for naked eye detection of mercuric ions, selected interfering ions and the like have no influence on the detection effect, the specificity recognition response to the mercuric ions is realized, the probe is relatively quick in response to the mercuric ions in an HEPES (pH =7.4) buffer system, the response can be completed within 5 min, the detection limit reaches 0.32 mu M, the probe has good selectivity and high sensitivity, the probe is successfully applied to the mercuric ion fluorescence imaging in cells and zebra fish, and the probe has good application prospect in the detection of mercuric ions in biological and environmental samples. |
priorityDate | 2018-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 64.