| abstract |
The present invention relates to a phenyl[a]indole[2,3-g]zoquinazine compound represented by the general formula (I), a preparation method thereof, a pharmaceutical composition and an application thereof. The application is specifically in the preparation and treatment of diseases related to proprotein convertase subtilisin Kexin-9 type (PCSK9), including prevention and treatment of hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, fatty liver Deformation, atherosclerosis, obesity and other metabolic disease drugs. |