| abstract |
The present invention relates to Ailanthus ketone, crystal form, derivative and preparation, preparation method and application as antiviral drug. The invention utilizes microbial fermentation technology to make the extraction rate of Ailanthus ketones reach more than 2.5%, and discloses that Ailanthus ketones, crystalline forms and preparations thereof have effects on hepatitis B virus, rotavirus, Norwalk virus, astrovirus and enterovirus. And the antiviral pharmacological data of influenza virus, its effect is significantly better than the current international clinical widely used first-line drugs for the treatment of hepatitis B "lamivudine, entecavir" and "Xiyanping injection" for the treatment of viral gastroenteritis. Developed as an antiviral drug. |