| abstract |
The invention discloses an application of a metal hydride/palladium compound system in preparing a 1, 3-dicarbonyl compound by series reaction of electron-deficient alkene compounds, wherein the reaction comprises the following steps: under the protection of nitrogen, suspending a palladium compound and a metal hydride in a solvent, stirring, adding an electron-deficient alkene compound, reacting at 0-100 ℃ for 0.3-10 hours, adding a saturated ammonium chloride aqueous solution to stop the reaction, extracting, evaporating to dryness, and purifying by column chromatography to obtain the product 1, 3-dicarbonyl compound. The hydride and palladium compound catalysts used in the invention are reagents which are easily obtained in a laboratory, and compared with the common hydrogen hydrogenation method, the method is easier to operate, higher in safety, mild in condition and high in reaction yield. |