http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109045310-B

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0002
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-04
filingDate 2018-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109045310-B
titleOfInvention Zwitterionic modified dendrimer composite material and preparation and application thereof
abstract The invention relates to a dendrimer composite material modified by zwitterions, and preparation and application thereof. Preparation: G5-DOTA- (PEG-RGD) aqueous solution, adding HAuCl 4 Solution, NaBH 4 Reducing, dripping gadolinium nitrate solution, stirring for 12h, finally dripping 1,3-PS for reacting for 24h, dialyzing, and freeze-drying to obtain the product. The method is simple, the prepared nano particles have long blood half-life period in a mouse body, can realize the tumor CT/MRI bimodal imaging function at the animal level, and has the industrialization and commercialization potentials.
priorityDate 2018-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 31.