http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109021020-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da2f79017444789d747982d4ab13b908 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-0086 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2018-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_28dc333ead6d4ba495c6e3f866c18b02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9e24f703c3d66324011338830757967 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_664e419c24c2bd48a8f71176a21544a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c67c55c63ecabfe72e4c683c78f43f7f |
| publicationDate | 2018-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109021020-A |
| titleOfInvention | 11,12-Dimethylbenzimidazole-1,8-naphthalimide-platinum complex and its preparation method and application |
| abstract | The invention discloses a 11,12-dimethylbenzimidazole-1,8-naphthalimide-platinum complex, a preparation method and an application thereof. The preparation method of the complex mainly includes the following steps: take the compound shown in the following formula (II) and the compound shown in formula (III) in an organic solvent, and carry out a coordination reaction under heating or without heating to obtain the target product. The inhibitory activity of the complex of the present invention on certain cancer cells is significantly higher than that of cisplatin, a commonly used anti-tumor drug, and its toxicity to normal human liver cells HL-7702 is lower. The structure of the complex of the present invention is shown in the following formula (I), and the structures of the compound shown in the raw material formula (II) and the compound shown in formula (III) involved in the preparation of the complex are as follows: |
| priorityDate | 2018-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.