http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109020976-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 2018-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109020976-B |
| titleOfInvention | Pyrimidotriazole-indole-containing compound and preparation method and application thereof |
| abstract | The invention discloses a pyrimidotriazole-indole compound with a general formula shown as I The invention also provides a preparation method and application of the compound. The in vitro BRD4 enzyme inhibition activity experiment proves that: the pyrimidotriazole-indole compound has potential inhibition effect on various tumor cells by inhibiting the enzyme activity of BRD4, and can be used as a lead compound for preparing antitumor drugs. In addition, the preparation method of the compound provided by the invention has the advantages of mild reaction conditions, simple operation and high yield. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114369098-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114369098-A |
| priorityDate | 2018-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 146.