http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109010847-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-644 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-428 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-428 |
| filingDate | 2018-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109010847-B |
| titleOfInvention | Apoferritin-benzothiazole compound and preparation method and application thereof |
| abstract | The invention discloses a apoferritin-benzothiazole compound and a preparation method thereof, which comprises the steps of filling ferritin liquid into a dialysis bag, placing the dialysis bag into sodium acetate dialysis buffer solution with the pH value of 4.5-5.5 and containing thioglycollic acid for dialysis, continuously introducing nitrogen in the dialysis process to keep an anaerobic environment, replacing the dialysis bag once every 20-25 min until the liquid in the dialysis bag is colorless, carrying out sterile filtration on the liquid in the bag by using a 0.22 mu m filter to prepare apoferritin mother liquor, and measuring the protein concentration of the mother liquor by using a BCA method; loading a benzothiazole compound into apoferritin by an in-situ production method of apoferritin and the benzothiazole compound to obtain an apoferritin-benzothiazole compound; the compound prepared by the invention has potential targeting anti-tumor effect. |
| priorityDate | 2018-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 120.