| abstract |
The invention provides a preparation method of a melatonin microneedle patch, which comprises the following steps: pouring a melatonin-containing polymer material aqueous solution on a mold with a micropore matrix, filling the polymer material aqueous solution into micropores on the mold, attaching a prefabricated backing layer to the mold, attaching the backing layer to the back of melatonin microneedles formed in the micropores, freezing, thawing, uncovering and drying to obtain the melatonin microneedle patch. |