http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108997426-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65522 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-655 |
| filingDate | 2018-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108997426-B |
| titleOfInvention | Flavone alkoxy phosphoramidate derivative targeting Hsp60, preparation and application |
| abstract | The invention discloses flavone alkoxy phosphoramidate derivatives targeting Hsp60, and preparation and application thereof. The preparation method of the derivatives is simple and easy to implement and low in cost. The invention designs and synthesizes a series of novel flavone alkoxy phosphoramidate derivatives with anti-tumor activity, which have obvious inhibiting and killing effects on breast cancer cells and liver cancer cells and have no obvious inhibiting effect on normal liver cells, develops the flavone alkoxy phosphoramidate derivatives which target Hsp60 and selectively resist tumor cell proliferation, and has good practical value and application prospect in the field of preparing anti-tumor drugs. |
| priorityDate | 2018-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 714.