http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108997216-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D221-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-26 |
| filingDate | 2018-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108997216-B |
| titleOfInvention | High clathrin crystal, preparation method, clathrin lyophilized powder for injection and preparation method |
| abstract | The present invention provides high-contrast crystals, and the X-ray powder diffraction pattern represented by the angle of 2θ±0.2° using Cu-Kα radiation is shown in FIG. 1 . The present invention also provides a method for preparing acetaminophen crystals. (1) Grinding the crude acetonitrile, passing through a 400-500 mesh sieve, adding it to anhydrous methanol, heating to 50-60° C. to dissolve, and reacting The time is 10 to 20 minutes; (2) then add dimethyl sulfoxide while stirring, and cool down to 10 to 25 ° C at the same time; (3) after adding, let stand and continue to cool down to ‑5 to 4 ° C, and grow crystals for 1 ~ After 2 hours, filter and dry to obtain crystals of high-conglanine. The present invention also provides the freeze-dried powder injection of high clathrin and a preparation method. The invention has the following beneficial effects: the clathrin crystals have good stability and wide application range, improve the bioavailability, and widen the selection range of the clatholin crystals in the preparation of pharmaceutical compositions. |
| priorityDate | 2018-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 70.