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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C313-06
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-18
filingDate 2018-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108976141-B
titleOfInvention Novel method for efficiently synthesizing chiral beta-amino acid
abstract The invention relates to a compound of formula (I)Method for the synthesis of compounds, chiral β -amino acids: the compound of aromatic aldehyde and chiral amine auxiliary agent form Schiff base, then the Schiff base is reduced to prepare intermediate compound of formula (IV), and then ester group and acyl are removed, and crystallization is carried out to obtain the product with optical activity. The method has the advantages of simple process, high yield, high purity, high optical purity of the product, no harsh reaction conditions, capability of obtaining different corresponding isomers by selecting different chiral auxiliary agents, small pollution and suitability for industrial production. Wherein the formula (I) and the formula (IV) are respectively as follows:
priorityDate 2018-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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