http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108949967-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6858 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6858 |
filingDate | 2018-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108949967-B |
titleOfInvention | Specific primer and kit for detecting cardiovascular disease drug gene polymorphism by liquid phase chip technology |
abstract | The invention discloses a primer group for simultaneously detecting 15 cardiovascular drug related target gene polymorphisms by using a liquid chip technology, which comprises 15 groups of primers, wherein each group of primers comprises a pair of specific amplification primers for detecting one target gene polymorphism and two ASPE primers respectively aiming at a wild type and a mutant type of the target gene. The invention also discloses a kit containing the primer groups and a using method thereof. The primer group and the kit thereof can amplify a target sequence in one-step PCR reaction, and detect related target gene polymorphism of 15 common cardiovascular drugs by combining MagPlex microspheres, and have high detection flux and high cost performance, so that once detection can provide medication guidance for patients with cardiovascular diseases, and provide laboratory basis for clinical rational medication; the kit has good sensitivity, stability and accuracy in practical application, is well matched with a gene sequencing result, and greatly reduces the detection cost. |
priorityDate | 2018-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 340.