http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108949154-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1029 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6486 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D221-14 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 |
filingDate | 2018-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108949154-B |
titleOfInvention | Application of small molecule containing naphthalimide as fluorescent probe in RNA detection and imaging |
abstract | The invention belongs to the technical field of cell imaging, and particularly relates to application of a small molecule containing naphthalimide as a fluorescent probe in RNA detection and imaging. The small molecular compound containing the naphthalimide is combined with RNA to have a fluorescence enhanced response, but the response to DNA under the same condition is very weak, so that the small molecular compound has very good selectivity in a solution state, can be used as a probe for distinguishing the RNA and the DNA, and can eliminate the DNA interference selective recognition RNA in the solution state and living cells; moreover, the small molecular compound can rapidly penetrate through cell membranes and nuclear membranes of living cells within two minutes, realizes fluorescence imaging of RNA in cytoplasm and nucleus, and has good biocompatibility. |
priorityDate | 2018-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.