http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108948180-A

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e7edc2841170dcdc290b9c6a21bf986f
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-695
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-695
filingDate 2018-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad4901c3415e7e41e31a272a34bfeea6
publicationDate 2018-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108948180-A
titleOfInvention Corticotropin preparation method
abstract The present invention relates to a kind of corticotropin preparation methods, belong to technical field of biochemical industry.Preparation method are as follows: the 0.6mol/L hydrochloric acid that the dehydrated alcohol and powder that pituitary dry powder uses powder to weigh 9 times weigh 3.6 times extracts 30 minutes under the conditions of 50 DEG C, feed liquid is cooled to -10 DEG C after extraction, it is centrifuged to obtain supernatant, 3 times of amount dehydrated alcohols of supernatant volume are added, pH4.1~4.4 are adjusted with sodium hydroxide solution, are centrifuged to obtain supernatant, adjust pH4.6~4.9 with sodium hydroxide solution, it is centrifuged to obtain precipitating, is lyophilized to obtain the final product.The beneficial effects of the present invention are: being extracted using the acetone in ethyl alcohol substitution traditional handicraft, reduces production craft step, reduce consumption of organic solvent.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109942697-A
priorityDate 2018-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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