abstract |
The present invention provides a diaminopyrimidine compound and a composition containing the compound. The present invention discloses a diaminopyrimidine compound represented by formula (I) and a compound containing the compound, or its crystal form, and a pharmaceutically acceptable salt , hydrates or solvates, stereoisomers, prodrugs or pharmaceutical compositions of isotopic variants. The diaminopyrimidine compound disclosed in the present invention and the composition comprising the compound have excellent inhibitory properties on protein kinases, and have better pharmacokinetic parameter characteristics, and can increase the drug concentration of the compound in the animal body to improve the efficacy of the drug and security. |