| abstract |
The invention discloses a 1,3-dihydroisobenzofuran derivative of the formula (I) and a synthesis method thereof. The aminoketene compound substituted by an ortho-alkyne group is used as a raw material, and under the action of a catalyst, the compound of the formula (I) 1,3-dihydroisobenzofuran derivatives. The preparation method of the invention has the advantages of mild reaction conditions, insensitive reaction to air, simple and easy-to-obtain raw materials, good substrate universality, simple post-treatment, excellent yield, and environmental friendliness. The present invention also provides the application of 1,3-dihydroisobenzofuran derivatives of formula (I) in molecular fluorescent probes. |