http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108947941-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D305-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-10 |
| filingDate | 2018-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108947941-B |
| titleOfInvention | Preparation method of 3-oxetanone |
| abstract | The invention discloses a preparation method of 3-oxetanone, belonging to the technical field of pharmaceutical chemical synthesis. Performing nucleophilic substitution reaction on a compound I, namely o-bromobenzoic acid, serving as an initial raw material and epoxy chloropropane under the action of a phase transfer catalyst to obtain a compound II; carrying out an oxidation reaction on the compound II under the action of an oxidant to obtain a compound III; and (3) carrying out hydrolysis reaction and intramolecular nucleophilic substitution reaction on the compound III under an alkaline condition to obtain a target compound IV, namely 3-oxetanone. The method can obtain the target product only by three steps, has easily controlled conditions, simple post-treatment, less side reaction and high yield, and meets the requirement of industrial production. The synthetic route is shown as a reaction formula. |
| priorityDate | 2018-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 71.