Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d94573ab2c57e8b193f3a22accddf9fe |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-20 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
filingDate |
2018-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad93e9dab7b5bc94c9df39b33deefd45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0e26576f6d971130937fa6f842240e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a940aed032d5a021e24115f91261972 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1fc0a2870f73a468e5f17d9ad5025e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9f8cbaac33560d5fed2126099b43bd7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d8b4f13553f1298010a9e8b4d56a640 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_768f61286199750e52db78179e0a23f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_737b23873df89ebbd935ebab840a3918 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6eb4be89bde5b25b948e8f3dccc8a44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6037c5726899d3ba6f011f5a1df24988 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5fe87526fc4155ba3b8ae77d0f0097b |
publicationDate |
2018-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-108947911-A |
titleOfInvention |
A kind of benzimidazole compound with anti-hepatitis B virus activity and antibacterial activity and its synthesis method and application |
abstract |
The invention discloses a benzimidazole compound with anti-hepatitis B virus activity and antibacterial activity, a synthesis method and application thereof. The structure of this benzimidazole compound is shown in general formula (I): Simultaneously, the synthesis method of the benzimidazole compound is also disclosed. It also discloses the application of the benzimidazole compound with anti-hepatitis B virus activity and antibacterial activity in the preparation of anti-hepatitis B virus medicine. The benzimidazole compounds disclosed in the present invention have certain anti-HBV biological activity and antibacterial activity, and the anti-hepatitis B virus activity is equivalent to the clinical anti-HBV drug tenofovir, and the antibacterial activity screening shows that the compound has better antibacterial activity against Staphylococcus aureus inhibitory activity. In terms of compound structure, synthesis method and biological activity, the invention has significant scientific significance and application prospects for the research and development of anti-hepatitis B innovative drugs and antibacterial drugs of new structural types. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114315734-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111303127-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111303127-B |
priorityDate |
2018-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |