http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108947911-A

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publicationDate 2018-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108947911-A
titleOfInvention A kind of benzimidazole compound with anti-hepatitis B virus activity and antibacterial activity and its synthesis method and application
abstract The invention discloses a benzimidazole compound with anti-hepatitis B virus activity and antibacterial activity, a synthesis method and application thereof. The structure of this benzimidazole compound is shown in general formula (I): Simultaneously, the synthesis method of the benzimidazole compound is also disclosed. It also discloses the application of the benzimidazole compound with anti-hepatitis B virus activity and antibacterial activity in the preparation of anti-hepatitis B virus medicine. The benzimidazole compounds disclosed in the present invention have certain anti-HBV biological activity and antibacterial activity, and the anti-hepatitis B virus activity is equivalent to the clinical anti-HBV drug tenofovir, and the antibacterial activity screening shows that the compound has better antibacterial activity against Staphylococcus aureus inhibitory activity. In terms of compound structure, synthesis method and biological activity, the invention has significant scientific significance and application prospects for the research and development of anti-hepatitis B innovative drugs and antibacterial drugs of new structural types.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114315734-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111303127-A
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priorityDate 2018-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103893178-A
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Total number of triples: 35.