http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108939090-B

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519
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filingDate 2018-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-01-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-01-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108939090-B
titleOfInvention Liposome, preparation method and application
abstract The invention discloses a liposome, a preparation method and application thereof. The liposome contains two siRNAs, wherein the two siRNAs are S respectively 37/38 、S 75/76 Said S 37/38 、S 75/76 The sequences of (A) are SEQ ID NO 1-2 and SEQ ID NO 3-4, respectively. The invention utilizes DSPE-PEG 2000 Modification of liposomes with MTX as ligand, simultaneous encapsulation of S 37/38 、S 75/76 The two siRNAs can achieve the purposes of targeting ovarian cancer cells, thereby inhibiting the proliferation of tumor cells and activating the apoptosis of the tumor cells.
priorityDate 2018-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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