http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108938601-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5089 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5047 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5073 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-501 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5015 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5026 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-62 |
filingDate | 2018-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108938601-B |
titleOfInvention | Metformin hydrochloride enteric-coated sustained-release pellet and preparation method thereof |
abstract | The invention provides a metformin hydrochloride enteric-coated sustained-release pellet and a preparation method thereof, wherein the sustained-release pellet sequentially comprises a sustained-release pellet core, a quick-release layer, an isolating layer and an enteric-coated layer from inside to outside, and is characterized in that a skeleton type sustained-release mechanism and an enteric-coated membrane controlled sustained-release mechanism are organically combined, an extrusion rounding process, a lamination medicine application process and a fluidized bed coating process are organically combined, key process parameters are strictly controlled, the metformin hydrochloride sustained-release pellet is prepared by adopting the process for the first time, the metformin hydrochloride sustained-release pellet not only avoids stimulation to the stomach of a human body, but also achieves the characteristic of sustained release and long effect, the drug effect is ensured for 24 hours, the drug compliance of a patient is improved, and the side effect is reduced. |
priorityDate | 2018-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 273.