http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108929874-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3181 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2509-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-315 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-16 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0693 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56966 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-115 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-115 |
| filingDate | 2018-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108929874-B |
| titleOfInvention | Nucleic acid aptamer specifically binding to cell with high-expression PDL1 protein and application of nucleic acid aptamer |
| abstract | The invention discloses an aptamer specifically binding to a cell highly expressing PDL1 protein, wherein the sequence of the aptamer comprises at least one of the following four sequences: A. a DNA sequence shown as SEQ ID No. 1; B. a DNA sequence which has more than 60 percent of homology with the DNA sequence shown in SEQ ID No.1 and can be specifically combined with cells of PDL1 protein with high expression; C. a DNA sequence which hybridizes with the DNA sequence shown in SEQ ID No.1 under strict conditions; D. an RNA sequence transcribed from the DNA sequence shown in SEQ ID No. 1. The invention also discloses a nucleic acid aptamer derivative. The invention also discloses an application of the aptamer or the aptamer derivative. The invention can be tightly combined with cells expressing PDL1 protein. |
| priorityDate | 2018-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.