http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108929251-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-12 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C319-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-48 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C319-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-52 |
| filingDate | 2018-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108929251-B |
| titleOfInvention | Method for direct trifluoromethylation of C (sp3) -H |
| abstract | The invention discloses a method for directly trifluoromethylylating C (sp3) -H. The method takes alkane as raw material, silver carbonate as catalyst, potassium persulfate as oxidant and trifluoro sulfinyl chloride and triphenylphosphine as trifluoromethylthio reagent, and synthesizes target compound in nitrile solvent at 30-80 ℃. The method has mild reaction conditions, good functional group tolerance and good selectivity, avoids using expensive trifluoromethylthio silver as a trifluoromethylthio reagent in the reaction process, reduces the production cost, and is suitable for large-scale production. The yield of the direct trifluoromethylthio of C (sp3) -H is more than medium, and the physical, chemical and biological properties of the compound can be significantly influenced due to the strong electronegativity and high lipophilicity. Can be applied to the fields of medicines, agricultural chemicals, materials and the like. |
| priorityDate | 2018-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.