http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108926714-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-06 |
| filingDate | 2018-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108926714-B |
| titleOfInvention | High-molecular gel for delivering pharmacological active substances to bladder cancer in bladder perfusion targeted manner and preparation method of high-molecular gel |
| abstract | The invention relates to a macromolecule gel for delivering pharmacological active substances by bladder perfusion and bladder cancer targeting and a preparation method thereof. The polymer gel mainly comprises dendrimer PAMAM capable of bearing pharmaceutical active substances and aldehyde polysaccharide which is targeted and adhered to bladder cancer. The invention also provides a macromolecule composite gel for targeted therapy of bladder cancer based on the macromolecule gel, and preferably, the macromolecule composite gel is loaded with a nano gold rod and gemcitabine. The composite gel has the following three advantages: firstly, the targeted sticking to the bladder cancer can slowly release the drug and prolong the action time of the drug, and meanwhile, the normal bladder epithelium drug has less retention and small side effect; secondly, the bladder cancer is treated by photo-heat, and tumor tissues can be killed and killed by the photo-heat ablation; thirdly, chemotherapy is combined with thermotherapy, and the tumor tissue killing effect of the chemotherapy is promoted through the thermotherapy. Meanwhile, compared with the traditional thermo-chemotherapy instrument, the device has low requirement on equipment and is easy to popularize. |
| priorityDate | 2018-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.