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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0604
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
filingDate 2018-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108913663-B
titleOfInvention A method for improving the in vitro developmental efficiency of nuclear transfer embryos
abstract The invention relates to the field of biotechnology, in particular to a method for improving the in vitro development efficiency of nuclear transfer embryos. The method for improving the in vitro development efficiency of nuclear transfer embryos provided by the present invention comprises: transferring the activated nuclear transfer reconstituted embryos into embryo culture medium containing BET protein inhibitor (+)-JQ1 for cultivation. The method of the invention can inhibit cell-directed transcriptional memory, promote the reprogramming of nuclear transfer embryos, and thereby improve the in vitro development efficiency of somatic cell nuclear transfer embryos.
priorityDate 2018-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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