http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108904540-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2603-18 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C249-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C251-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C249-16 |
| filingDate | 2018-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108904540-B |
| titleOfInvention | Extraction and purification method and application of alkaloid in ground beetle |
| abstract | The invention belongs to the technical field of chemical extraction of traditional Chinese medicines, and particularly relates to a method for extracting and purifying alkaloid in Eupolyphaga sinensis Walker and application thereof. The invention provides an extraction method for extracting alkaloid from eupolyphaga sinensis, a purification method for the alkaloid obtained by the extraction method, application of the alkaloid obtained by the extraction method or the purified alkaloid obtained by the purification method in bacteriostasis, and application of the alkaloid obtained by the extraction method or the purified alkaloid obtained by the purification method in inhibition of gastric cancer cell growth. According to the extraction and purification method provided by the invention, GBA18 can be obtained through separation; the experimental determination shows that the obtained product has good effects on inhibiting gastric cancer and inhibiting bacteria, and simultaneously, half of lethal dose and minimum lethal dose belong to the safe use range recommended by Chinese pharmacopoeia; solves the technical defects that the effective components in the ground beetles are not clear and the application of the ground beetles is seriously limited in the prior art. |
| priorityDate | 2018-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 72.