http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108893473-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-10 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-907 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-90 |
| filingDate | 2018-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108893473-B |
| titleOfInvention | Rab23 gene knockout in epidermal stem cells by using CRISPR-Cas system |
| abstract | The invention provides RAB23 gene editing for epidermal stem cells by using a CRISPR-Cas system, and particularly relates to establishment of an epidermal stem cell line with a built RAB23 gene knockout function, which is used for follow-up research of skin squamous cell carcinoma. A specific gRNA is constructed and obtained, and the gene editing efficiency of CRISPR/Cas9 in epidermal stem cells to RAB23 can be obviously improved. The epidermal stem cell RAB23 knockout plasmid provided by the invention has better genetic stability and higher targeting efficiency. |
| priorityDate | 2018-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 430.