http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108888765-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0057 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5015 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50 |
| filingDate | 2018-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108888765-B |
| titleOfInvention | Preparation method of methylene blue aggregate-releasing silicon dioxide/shellac composite particle containing methylene blue |
| abstract | The invention provides a preparation method of a methylene blue aggregate-containing silicon dioxide/shellac composite particle, belonging to the technical field of chemical raw material production. Adding ammonia water, methylene blue and ethyl orthosilicate into a mixed solution of water and ethanol, stirring for 4 hours, centrifuging, washing, drying at 70 ℃, dispersing the prepared silicon dioxide particles containing the methylene blue into a shellac solution, dropwise adding a phosphate buffer solution, stirring for 1 hour, centrifuging, washing, drying at room temperature, and carrying out heat treatment on the prepared silicon dioxide/shellac composite particles containing the methylene blue at 90-180 ℃ for 24 hours to obtain the silicon dioxide/shellac composite particles containing the methylene blue, wherein the silicon dioxide/shellac composite particles containing the methylene blue aggregate are released. The method has simple process, low raw material price and easy industrial production, and the obtained particles have good biocompatibility and are easy to degrade. Methylene blue is released from the interior of the particle into solution mainly in the form of dimers and trimers. |
| priorityDate | 2018-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.