http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108888616-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44ae178fe5ea1fd193b8e5e1baf1ab3b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-18 |
| filingDate | 2018-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3b7f44025e0db6bca20e77049bb6b29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c39094bc0b991025657c71ae5f29df15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51af59b7e9e719b45d0dec49b4c3a7af |
| publicationDate | 2018-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108888616-A |
| titleOfInvention | Application of the isoliquiritigenin in treatment acute pancreatitis drug |
| abstract | The invention proposes application of the isoliquiritigenin in preparation treatment acute pancreatitis (AP) drug.The isoliquiritigenin is by alleviating the relevant GRP78 albumen of pancreatic tissue er stress induced by AP, ATF6 albumen, CHOP albumen increases to alleviate the reaction of the irritability of endoplasmic reticulum, increase the autophagy to inhibit pancreatic tissue by the marker protein Beclin-1 albumen and LC3II albumen of alleviating the pancreatic tissue autophagy induced by AP, and it can inhibit to inhibit the expression of apoptotic proteins (c-caspase3), to play the role for the treatment of acute pancreatitis, it is in particular in the reduction of amylase and lipase content in serum and alleviates tissue edema caused by pancreatitis, reduce histopathological scores. |
| priorityDate | 2018-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 92.