http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108865963-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-66 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-125 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 |
| filingDate | 2018-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108865963-B |
| titleOfInvention | Genetic operation method for artificially controlling spontaneous mutation rate of bacillus subtilis and application thereof |
| abstract | The invention belongs to the technical field of biology, and particularly relates to a genetic operation method for artificially controlling spontaneous mutation rate of bacillus subtilis and application thereof. By combining the operon responsible for the mismatch repair system of Bacillus subtilis MutSL Under the regulation of xylose inducing promoter and repressor protein, and constructing corresponding recombinant plasmid for inducing expression, and its application Spizizen Integrating the recombinant plasmid into the genome of the strain by double exchange, obtaining a target engineering strain by positive and negative screening, and adjusting the operon of a mismatch repair system by different xylose addition concentrations MutSL Different expression levels ， Further realizing the artificial control of the spontaneous mutation rate of the bacillus subtilis. |
| priorityDate | 2018-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 520.