http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108864164-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-0812 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-0827 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-08 |
| filingDate | 2018-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108864164-B |
| titleOfInvention | Synthesis method of primary amine-guided 2-alkynyl indole compound |
| abstract | The invention discloses a synthetic method of a primary amine-guided 2-alkynyl indole compound. The synthesis method comprises the following steps: in the reactor, 2- (1) is added H The preparation method comprises the following steps of (1) reacting an-indole-1-yl) aniline compound, alkyne halide, a palladium salt catalyst, alkali and a solvent at 80-110 ℃ under stirring, and separating and purifying reaction liquid to obtain the 2-alkynyl indole compound. The method of the invention develops 2- (1) H The cross coupling reaction of-indole-1-yl) aniline and alkyne halide constructs a series of highly functionalized 2-alkynyl indole compounds, and the reaction takes water as a solvent, thereby meeting the development requirements of green organic chemistry. In addition, the main characteristics of the reaction are simple and easily available raw materials, safe operation, good regioselectivity and wide substrate universality. |
| priorityDate | 2018-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 87.