http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108864123-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-147 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-147 |
| filingDate | 2018-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108864123-B |
| titleOfInvention | Synthetic method of stemona alkaloid |
| abstract | The invention discloses a synthesis method of stemona alkaloid, belonging to the technical field of chemical synthesis. The method is characterized in that: boron trifluoride diethyl etherate (3:1 molar equivalent ratio) is added to (C-10-0) R , E ) -methyl-4-hydroxy-7- (1) H -pyrrol-1-yl) heptyl-2-enoic acid methyl esterTo the dichloroethane solution, the reaction mixture was warmed to room temperature and stirred (12-36 hours). To obtain (3 a) R ,10b R ) -3a,4,5, 6-tetrahydro-1 H -furan [3,2-c]Pyrrolidine [1,2-a ]]Azepine-2 (10 b) H ) -a ketone. The invention provides a synthesis strategy for efficiently synthesizing the stemona alkaloid parvistemonine, and lays a foundation for further pharmacological activity and chemical and biological research of the natural product. |
| priorityDate | 2018-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 120.