http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108864109-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_900294f396b66b4694648daa18c8a4c8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2018-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14061f673664f0b1e09a919f210d10f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78f38227d0b747b4ada42adf8388c691 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_915600f53100118dbd03b4ba877f6c96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a01926e1d79baa27684a9b51df7ccce http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6e1ddc96fa652575285bd4bb1965280 |
| publicationDate | 2018-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108864109-A |
| titleOfInvention | The synthetic method and application of amino-contained Chao Geer alkali derivant, binaphthol-Chao Geer alkali amine Shiff base derivative |
| abstract | The synthetic method and application of amino-contained Chao Geer alkali derivant, binaphthol-Chao Geer alkali amine Shiff base derivative, the structural formula of the amino-contained Chao Geer alkali derivant is as shown in following formula 2, by amino-contained Chao Geer alkali, N- bromo-succinimide, azodiisobutyronitrile and acetonitrile solution in reaction is made in a heated condition in container.Amino-contained Chao Geer alkali derivant of the invention is to triple negative breast cancer (MDA-MB-231), breast cancer (MCF-7), human lung cancer (A549) cell strain has preferable inhibitory effect, and it is lower to the toxicity of normal human cell, it has broad application prospects on the specific drug for preparing anti-lung cancer and breast cancer of new generation；Binaphthol-Chao Geer alkali amine Shiff base derivative of the invention can be used as catalyst in the reaction for preparing thiocarbamoyl imidazole alkanone analog derivative. |
| priorityDate | 2018-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 48.