http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108853569-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2305-08 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L26-0085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L26-0023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-0036 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-0031 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L26-009 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J3-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L26-008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J3-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-0042 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L26-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L5-08 |
| filingDate | 2018-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108853569-B |
| titleOfInvention | Covalent cross-linked hyaluronic acid aerogel, hydrogel thereof and preparation method |
| abstract | The invention provides hyaluronic acid aerogel formed by covalent crosslinking, hydrogel thereof and a preparation method thereof, belonging to the field of tissue engineering and medical materials. The method comprises the steps of preparing a hyaluronic acid aqueous solution by using hyaluronic acid as a raw material, using 1, 4-butanediol diglycidyl ether, or ethylene glycol diglycidyl ether, or polyethylene glycol diglycidyl ether (n is 10, the molecular weight is 500) as a cross-linking agent, promoting the cross-linking agent and the hyaluronic acid to carry out chemical cross-linking through covalent bonds by using a freeze-drying technology to prepare a covalently cross-linked hyaluronic acid aerogel, soaking the covalently cross-linked hyaluronic acid aerogel in purified water, and swelling the covalently cross-linked aerogel by absorbing water to obtain the covalently cross-linked hyaluronic acid hydrogel. The covalently crosslinked hyaluronic acid aerogel prepared by the method has good liquid absorption performance, can quickly absorb water and swell into the covalently crosslinked hyaluronic acid aerogel, and the covalently crosslinked hyaluronic acid aerogel obtained by water absorption and swelling of the covalently crosslinked aerogel has good stability and enzyme degradation resistance. Has good application prospect in the fields of tissue engineering and medical materials. |
| priorityDate | 2018-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 77.