http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108840794-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C49-825 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C49-255 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-825 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-255 |
| filingDate | 2018-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108840794-B |
| titleOfInvention | Novel curcumin drug cocrystal and preparation method thereof |
| abstract | The invention relates to a curcumin-coniferol pharmaceutical co-crystal and a preparation method thereof. The eutectic is formed by combining curcumin and abietyl phenol through non-covalent interaction. The eutectic belongs to the triclinic system and has an axial length a =15.652~15.852Å， b =11.476~11.676Å， c =7.226~ 7.426A, axial angle α =97.37°~97.57°， β =96.29°~96.49°， γ =100.46 ° -100.66 °, eutectic in the X-ray powder diffraction pattern at diffraction angle 2 θ There are major peaks at =8.757 °, 17.142 °, 20.304 °, 22.512 °, 23.227 °, 24.614 °, 26.028 °. The co-crystals of the present invention may be prepared by a solvent-assisted milling process. The invention provides possibility for crystal modification on the premise of not changing the covalent structure of curcumin. |
| priorityDate | 2018-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.