abstract |
The present invention provides a method of preparing a functionalized polymeric chromatographic medium comprising: (I) providing two or more nonwoven sheets, one stacked on top of the other, each of said sheets comprising one or more polymeric nanofibers, (II) simultaneously heating and pressing the stacked sheets to fuse the contact points between the nanofibers of adjacent sheets, and (III) combining the pressed and heated product with a reagent phase contacting to functionalize the product of step (II) into a chromatographic medium. |