http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108837144-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-09 |
| filingDate | 2018-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108837144-B |
| titleOfInvention | Application of triptorelin |
| abstract | The application belongs to the field of medicines, and discloses application of triptorelin, in particular application of triptorelin in preparation of a medicine for treating depression. Experiments show that in forced swimming experiments, triptorelin can obviously reduce chronic restriction stress, lipopolysaccharide, plantar injection CFA and early social isolation induced immobility time of depression model mice, and has obvious improvement effect on the depression model mice. Meanwhile, triptorelin can obviously increase the expression of mouse hippocampal BDNF and neuron synaptic plasticity related genes c-fos, egr1, arc and npas4 induced by chronic limiting stress. Therefore, the triptorelin has obvious anti-depression activity, can be used for preparing the medicament for treating depression, and has higher clinical application value and development prospect. |
| priorityDate | 2018-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 241.