| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5a800e578021942a6d501c28cee868eb |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57484
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57438
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-04 |
| filingDate |
2018-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3db0cb2eebe31888b739924b7191d07e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_979bbc5704fdf26b62c18adb1c159a15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7455aa9aabf3a7a829555d26e46b0a8e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32b10f5184f88591f9ca2a5207e49429 |
| publicationDate |
2018-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-108823315-A |
| titleOfInvention |
Application of reagents for detecting fen1 gene expression level in preparation of reagents for diagnosing and predicting invasion and metastasis of liver cancer |
| abstract |
The invention relates to the field of biotechnology, in particular to the application of reagents for detecting the expression level of fen1 gene in the preparation of reagents for diagnosing and predicting the invasion and metastasis of liver cancer, and the application of inhibitors of fen1 gene in the preparation of drugs for inhibiting the invasion and metastasis of liver cancer. The present invention discovers for the first time that the fen1 gene is related to the occurrence and development of liver cancer: the present invention proves that changing the expression level of FEN1 can affect cell invasion and metastasis through interference experiments; animal experiments show that the expression of FEN1 can promote the metastasis of liver cancer. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111349706-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111349706-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112575067-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112575067-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115290774-A |
| priorityDate |
2018-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |