http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108823144-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-999 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-25 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-069 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-44 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2018-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108823144-B |
titleOfInvention | Inhibit the excretion body active ingredient and its preparation method and application of endothelial cell migration |
abstract | The present invention relates to a kind of excretion body active ingredients and its preparation method and application for inhibiting endothelial cell migration, and preparation method is the following steps are included: separating primary umbilical vein endothelial cell and carrying out cell culture and passage;Anisodamine Human Umbilical Vein Endothelial Cells are added into the culture fluid of endothelial cell of secondary culture to be pre-processed, simultaneously TNF-α continuation Cultured endothelial cell is added in the culture fluid of endothelial cell then more renewed;Excretion body is extracted in the culture fluid of endothelial cell containing TNF-α obtained from after Endothelial cell culture;The identification of excretion body.With the excretion body active ingredient prepared by preparation method of the present invention for inhibiting endothelial cell migration and its application in anti-tumor drug.Preparation method of the present invention is simple, and the excretion body of preparation is able to suppress the migration of endothelial cell. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112029705-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112029705-A |
priorityDate | 2018-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.