| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9a38a062781e4e44718aa12bb10a153b |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65616 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6561 |
| filingDate |
2018-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e5ba337cb446cc7ba9acb90414075ee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e3e5dc864331ad85082b683c795d828
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_edc0b0c35984e82ab86da9c811af5905 |
| publicationDate |
2018-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-108822149-A |
| titleOfInvention |
A kind of preparation method of key intermediate of tenofovir alafenamide fumarate |
| abstract |
The present invention belongs to the field of medicine synthesis, and relates to a preparation method of a medicine intermediate, in particular to a preparation method of a key intermediate of tenofovir alafenamide fumarate. The present invention provides a new method for preparing tenofovir alafenamide fumarate key intermediate 2 with high diastereomer purity. The method has the advantages of short reaction time, few by-products, simple operation and high product quality Good quality, high reaction yield, more suitable for industrial production and other characteristics. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111484527-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111484528-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115651023-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110272455-A |
| priorityDate |
2018-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |