http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108796078-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 |
filingDate | 2018-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108796078-B |
titleOfInvention | A primer and probe set for gastrointestinal cancer diagnosis, detection or screening |
abstract | The invention belongs to the field of biomedicine, and in particular relates to a primer and probe set for diagnosing, detecting or screening of gastrointestinal cancer, the primer comprises a forward primer and a reverse primer of SFRP2, and the probe is SFRP2 probe, the forward primer of SFRP2 comprises any sequence in SEQ ID: 1-16, and the reverse primer of SFRP2 comprises any sequence in SEQ ID: 17-30. Compared with the prior art, the beneficial effects of the present invention are: by extracting the DNA in the biological sample and adopting the fluorescence quantitative PCR technology to detect whether the biological sample contains the methylated SFRP2 gene, so as to judge whether the risk of gastrointestinal tumor is present. ; The SFRP2 methylation sequence can be well detected, and the detection sensitivity can reach 10 copies/reaction; the methylated SFRP2 gene can clearly distinguish cancer samples and normal samples of colorectal cancer, gastric cancer, esophageal cancer and other gastrointestinal cancers. |
priorityDate | 2018-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.