http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108795895-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f347d94f0db9282af2f687ecf86b6bb7 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C02F2101-12 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y111-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0065 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C02F3-342 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C02F101-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C02F3-34 |
| filingDate | 2018-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0066df52d257427583938d6e88491223 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25dad40738c8ff8b6e4d766cfcca6b74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03aa8d725539987aa1a1d066e071bb36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b5486a145f708c7133b813550f9b4c8 |
| publicationDate | 2018-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108795895-A |
| titleOfInvention | A kind of dehalogenation peroxidase and the preparation method and application thereof |
| abstract | The invention belongs to artificial metal enzyme field, a kind of efficient dehalogenation peroxidase and the preparation method and application thereof is disclosed.Dehalogenation peroxidase of the present invention is using the myoglobins of transport oxygen function as Protein Molecular Design skeleton, by myoglobins heme active immediate vicinity, 43 sport tyrosine, simultaneously by 64 Histidine mutagenesis at acid aspartic acid, to double mutant body protein F43Y/H64D Mb of the structure with catalysis, amino acid sequence is as shown in SEQ ID NO.1.Artificial dehalogenation peroxidase of the present invention, can be in low H 2 O 2 Catalysis halogenated phenols is oxidized to the quinones product of low toxicity in the concentration lower several seconds, reach dehalogenation effect, similar in catalyzed conversion number, greatly improve affinity of the double mutant protein to halogenated phenols, its catalytic efficiency is significantly improved than simple point mutation body protein, so as to be widely applied to the improvement of halogenated phenols organic pollution. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114891092-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114891092-B |
| priorityDate | 2018-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 150.