http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108794389-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-71 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-71 |
| filingDate | 2018-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108794389-B |
| titleOfInvention | Preparation method of 2,3,5, 6-tetrachloro-4-methylsulfonylpyridine |
| abstract | The invention discloses a preparation method of 2,3,5, 6-tetrachloro-4-methylsulfonylpyridine, which comprises the steps of dissolving pentachloropyridine in tetrahydrofuran, dropwise adding sodium methanethiol aqueous solution at normal temperature, after the reaction is finished, phase splitting, and distilling at normal pressure to recover tetrahydrofuran to obtain an organic phase; adding organic acid and a catalyst into the organic phase, dropwise adding hydrogen peroxide in sections, and cooling and crystallizing after the reaction is finished to obtain the target product 2,3,5, 6-tetrachloro-4-methylsulfonylpyridine. The invention solves the problems of difficult separation and purification of products, high production cost, large amount of three wastes, large foul smell of intermediates, expensive oxidant and the like in the prior art, adopts the green oxidant, does not cause secondary pollution to the environment, optimizes the reaction condition and effectively improves the purity and yield of the target product; meanwhile, the raw materials of the oxidant are cheap and easy to obtain, the selectivity is good, the side reaction is less, the product yield is high, the reaction condition is mild and easy to control, and the process operation is simple and easy to industrialize. |
| priorityDate | 2018-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.