http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108785318-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7032 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7032 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2017-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108785318-B |
titleOfInvention | Application of phenylpropanoid glycoside compounds in preparation of IDO inhibitor |
abstract | The invention belongs to the field of medicines or health-care products, and particularly relates to an application of phenylpropanoid glycoside compounds and pharmaceutically acceptable derivatives thereof in preparation of IDO inhibitors. According to the invention, researches show that the inhibitory activity of verbascoside and cistanchid on intracellular IDO is superior to that of a positive control drug 1-methyltryptophan (1-MT) on intracellular IDO, the inhibitory activity of the verbascoside and the cistanchid on intracellular IDO has obvious IDO inhibitory activity, and the verbascoside and the cistanchid can be used for treating cancers, Alzheimer's disease, ankylosing spondylitis, autoimmune diseases, bacterial infection, cataract, mood disorders, depression or anxiety. |
priorityDate | 2017-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 59.