abstract |
The invention belongs to the field of medicines or health care products, and specifically relates to the use of phenylpropanoid glycosides and pharmaceutically acceptable derivatives thereof in preparing IDO inhibitors. The present invention finds through research that the inhibitory activity of verbascoside and cistancheside D on intracellular IDO is better than that of the positive control drug 1-methyltryptophan (1-MT) on intracellular IDO, and has significant The inhibitory activity of IDO can be used to treat cancer, Alzheimer's disease, ankylosing spondylitis, autoimmune disease, bacterial infection, cataract, mood disorder, depression or anxiety. |