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filingDate 2017-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108780089-B
titleOfInvention Methods for Assessing Protein Interactions Between Cells
abstract Methods are provided for the detection and quantitative measurement of protein-protein interactions between proteins present on different cell surfaces using sensitive antibody-based assays. Antibodies specific for each target protein are labeled directly or detected by labeled secondary antibodies. Antibodies are labeled with detectable tags that are releasable when target proteins are brought into proximity with each other. Also provided are methods of using the assay to detect protein-protein interactions between target proteins of interest to advance the diagnosis, prognosis, and treatment of cancer. Also provided are methods of screening test reagents that affect protein-protein interactions.
priorityDate 2016-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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