| abstract |
The present invention provides hydroxypropylthiazolidine carboxamide derivatives of formula (I), namely (2S)-3-([1,1'-biphenyl]-4-ylsulfonyl)-N-[(1S) ‑3‑Hydroxy‑1‑phenylpropyl]‑l,3‑thiazolidine‑2‑carboxamide L‑valine ester, salts and crystalline polymorphs thereof. The compounds inhibit the prostaglandin F receptor (PGF2α) and are useful in the treatment of conditions such as premature labor or dysmenorrhea in early pregnancy. |