abstract |
Compositions and methods useful for enhancing skin penetration of drug nanoparticles are disclosed. The composition may be hydrophobic and include a hydrophobic carrier, a volatile silicone fluid, and drug nanoparticles. Also disclosed are methods for inhibiting crystal growth of drug nanoparticles in aqueous or hydrophobic carriers. In addition, methods of topical treatment of psoriasis using compositions containing paclitaxel or other taxane nanoparticles are disclosed. |