http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108760950-B

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-06
filingDate 2018-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108760950-B
titleOfInvention A kind of method for determination of nitrofuran metabolites
abstract The invention discloses a method for determining nitrofuran metabolites, which comprises a derivatization step: taking a sample to be tested, adding an organic solution of dimethylaminonaphthalenesulfonyl chloride, heating in a water bath to obtain a derivatized sample; and a filtering step: filtering the derivatized sample , obtain the impurity-removing sample; determination step: carry out liquid chromatography tandem mass spectrometry determination on the impurity-removing sample. The method for determining nitrofuran metabolites uses dimethylaminonaphthalenesulfonyl chloride to derivatize the sample to be tested, and the nitrofuran dimethylaminonaphthalenesulfonamide compound generated after derivatization is not easy to be hydrolyzed and has good stability, so it does not need to use internal The target compound can be measured, thereby reducing the cost of detection, while the detection time of this method is shortened and the efficiency is higher.
priorityDate 2018-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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